Where Does The Susquehanna River Start And Where Does It End. Siskëwahane) is a major river located in the northeastern united states. The susquehanna and its hundreds of tributaries drain 27,510 square miles, an area nearly the size of south carolina, spread over parts of the states of new york, pennsylvania, and maryland.

The river meanders 444 miles from its origin at otsego lake near cooperstown, new york and empties into the chesapeake bay at havre de grace, maryland. The dam is a joint initiative of paraguay and argentina. It flows 444 miles through central pennsylvania and into northern maryland, where it empties into the chesapeake bay.